While research on the exact mechanisms and pathways of the sunshine vitamin’s effect on breast cancer are ongoing, evidence consistently shows a clear association between circulating vitamin D [i.e., 25(OH)D serum vitamin D levels] and breast cancer risk.
In a 2015 case-control study from Breast Cancer Research and Treatment, women deficient in vitamin D [i.e., with 25(OH)D levels below 20 ng/ml] had a 27% higher risk5 of breast cancer than women with sufficient vitamin D levels. But while clinical vitamin D sufficiency is defined as 25(OH)D levels above 30 ng/ml, other research indicates that higher levels provide greater protection against breast cancer risk.
Case in point: In one pooled analysis from Anticancer Research, a serum 25(OH)D level of 47 ng/ml was found to lower breast cancer risk by 50%6. This aligns with what mindbodygreen has found after speaking to leading endocrinologists, RDs, and longevity experts—a truly optimal vitamin D status of 50 ng/ml or higher is the goal for thriving health and well-being.